Advances in Cardiac Genetic Testing
Look through past and recent research material in the field of cardiovascular diseases typically focusing on genetics and genome testing below.
In spite of tremendous advances in diagnosis and treatment of cardiovascular disease in the young, our understanding of its cause is still incomplete. Recent studies have reported pleiotropic cardiac malformations resulting from mutations in transcription factors, a family of proteins known to play important roles in many aspects of development. Further evaluation of these important causes of cardiovascular disease in the young promises new insight into embryology of cardiac development and improved understanding of the pathophysiologic basis of cardiovascular disease in the young.
In recent years, major advances have been made in the application of “omics” technologies to cardiovascular science and medicine. The year 2011 was no exception, with a number of groundbreaking studies published ranging from the execution of ever-larger genome-wide association studies (GWAS) to the discovery of promising new diagnostic and therapeutic approaches.
Advances in the science of the human gene and its application to medical care are the breaking wave of much of medicine. In its most basic definition, genomics seeks to find the relationship between particular genes or groups of genes and the functions of cells and organs in health and disease.
Among the nation’s trailblazers in genomics research and application is the McCormick Genomics Center at The George Washington University, one of the few centers in the world to focus on cardiovascular genomic research. This research will enable doctors to profile an individual’s genetic make up and predict whether they are at risk for cardiovascular disease and what treatment will work best. By identifying the genes that can cause and cure heart disease, researchers hold in their hands the potential for personalized medicine.